The prevalence of Co-infection with HCV and HDV in HBV infected patients in Golestan province of Iran

مجله دانشگاه علوم پزشکی گرگان

Gholamreza Roshandel¹  Abdolvahab Moradi¹  Danyal Roshandel¹  Saba Besharat¹  Hamid Reza Joshaghani¹  Sima Besharat¹  Abbas Ali Kashtkar¹  Ali Jabbari¹  Shahryar Semnani¹  Ahmad Danesh¹  Seyed Ahmad Hosseini¹  Khodaberdi Kalavi¹  Mohammad Javad Kabir¹  Seyed Mahdi Sedaghat¹  Nafiseh Abdolahi¹ 

[1] ;

关键词: HBV;    HCV;    HDV;    Golestan;   

DOI  :  

来源: DOAJ

【 摘 要 】

Background & Objective: Hepatitis B virus (HBV) infection is one of the most important health problems all over the world. This study was conducted to determine the co-infection of hepatitis C virus (HCV), hepatitis D virus (HDV) in HBV infected patients in Golestan province of Iran. Materials & Methods: This population based cross sectional study was done in 2004. 139 HBsAg positive cases were assessed for co-infection with HCV and HDV. Serologic tests were done by ELISA method using available kits. Data were analyzed by SPSS-12 and STATA8 software. P-values of less than 0.05 were considered as significant. Results: Sixty eight (48.9%) of 139 cases were males and 71 (51.1%) were females. The mean (±SD) of participant's age was 41.89 (±11.3) years (range: 25-64 years). Anti-HCV and Anti-HDV antibodies were positive in 17 (12.3%) and 8 (5.8%) cases, respectively. Females were more infected with HCV and HDV than males. But the differences were not significant. Conclusion: The prevalence of co-infection with HCV and HDV in HBV infected cases is relatively high and notable in Golestan province of Iran. Because of negative effects of these co-infections in clinical outcome of the disease, it is recommended to assess possible HCV and HDV infection in individuals with HBV infection. This may result in more efficient management of the disease.

【 授权许可】

Unknown