Emerging Technologies for Dentin Caries Detection—A Systematic Review and Meta-Analysis

Journal of Clinical Medicine

Diana Lungeanu¹  Virgil-Florin Duma²  Meda Lavinia Negrutiu³  Christa Serban³  Cosmin Sinescu³  Emanuela Lidia Craciunescu³  Sergiu-David Bota³  Claudia C. Cotca⁴ 

[1] Center for Modeling Biological Systems and Data Analysis, “Victor Babes” University of Medicine and Pharmacy of Timisoara, 300041 Timisoara, Romania;Research Center in Dental Medicine Using Conventional and Alternative Technologies, “Victor Babes” University of Medicine and Pharmacy of Timisoara, 300070 Timisoara, Romania;School of Dental Medicine, “Victor Babes” University of Medicine and Pharmacy of Timisoara, 300070 Timisoara, Romania;Washington Institute for Dentistry & Laser Surgery, Chevy Chase, MD 20815, USA;

关键词: dental caries;    non-cavitated dentin caries;    diagnosis;    occlusal caries;    proximal caries;    permanent teeth;   

DOI  :  10.3390/jcm11030674

来源: DOAJ

【 摘 要 】

This systematic review and meta-analysis aimed at assessing the diagnostic accuracy of emerging technologies, such as laser fluorescence (LF), transillumination, light-emitting diode devices, optical coherence tomography (OCT), alternating current impedance spectroscopy, fluorescence cameras (FC), photo-thermal radiometry, and modulated luminescence technology. In vivo and in vitro results of such non-ionizing, non-invasive, and non-destructive methods’ effectiveness in non-cavitated dentin caries detection are sometimes ambiguous. Following the PRISMA guidelines, 34 relevant research articles published between 2011–2021 were selected. The risk of bias was assessed with a tool tailored for caries diagnostic studies, and subsequent quantitative uni- and bi-variate meta-analysis was carried out in separate sub-groups according to the investigated surface (occlusal/proximal) and study setting (in vivo/in vitro). In spite of the high heterogeneity across the review groups, in vitro studies on LF and FC proved a good diagnostic ability for the occlusal surface, with area under the curve (AUC) of 0.803 (11 studies) and 0.845 (five studies), respectively. OCT studies reported an outstanding performance with an overall AUC = 0.945 (four studies). Promising technologies, such as OCT or FC VistaProof, still need well-designed and well-powered studies to accrue experimental and clinical data for conclusive medical evidence, especially for the proximal surface. Registration: INPLASY202210097.

【 授权许可】

Unknown