Changing Trends in Hospital Admissions for Pulmonary Embolism in Spain from 2001 to 2018

Journal of Clinical Medicine

Manuel Monreal¹  Romana Albaladejo-Vicente²  José Javier Zamorano-Leon²  Rodrigo Jimenez-Garcia²  David Carabantes-Alarcon²  Valentín Hernández-Barrera³  Ana Lopez-de-Andres³  Javier de de Miguel-Diez⁴  David Jiménez⁵ 

[1] Department of Internal Medicine, Hospital Universitari Germans Trias i Pujol, CIBER de Enfermedades Respiratorias (CIBERES), Badalona, 08916 Barcelona, Spain;Department of Public Health & Maternal and Child Health, Faculty of Medicine. Universidad Complutense de Madrid, 28040 Madrid, Spain;Preventive Medicine and Public Health Teaching and Research Unit, Health Sciences Faculty, Rey Juan Carlos University, 28922 Alcorcón, Madrid, Spain;Respiratory Department, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Facultad de Medicina, Universidad Complutense de Madrid, CIBER de Enfermedades Respiratorias (CIBERES), 28040 Madrid, Spain;Respiratory Department, Ramón y Cajal Hospital and Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Medicine Department, Universidad de Alcalá, CIBER de Enfermedades Respiratorias (CIBERES), 28038 Madrid, Spain;

关键词: pulmonary embolism;    trends;    incidence;    in-hospital mortality;    COPD;    diabetes;   

DOI  :  10.3390/jcm9103221

来源: DOAJ

【 摘 要 】

(1) Background: The aims of this study were to examine trends in the incidence, clinical characteristics, and in-hospital outcomes of patients hospitalized with pulmonary embolism in Spain and to identify factors associated with in-hospital mortality (IHM). (2) Methods: We included all patients who were hospitalized for pulmonary embolism between 2001 and 2018. Data were collected from the Spanish National Hospital Discharge Database. (3) Results: We identified 241,821 hospitalizations for pulmonary embolism during the study period. The incidence of pulmonary embolism increased from 20.49 cases per 100,000 inhabitants in the period 2001–2002 to 35.9 cases in the period 2017–2018 (p < 0.001). After controlling for possible confounders, there was a significant increase in the incidence over the study period (adjusted incidence rate ratio 1.53, 95% Confidence Interval I 1.51–1.56). The median length of hospital stay was 11 days in the period 2001–2002, decreasing to seven days in the period 2017–2018 (p < 0.001). For the total time period, the crude IHM rate was 9.51%. After multivariable adjustment, IHM decreased significantly over time. The IHM was significantly higher in women, in patients suffering from more comorbidities, and in those with a massive pulmonary embolism. (4) Conclusions: Our results revealed an increase in the incidence of pulmonary embolism hospitalizations from 2001 to 2018 in Spain, with older patients being the most affected.

【 授权许可】

Unknown