The impact of cisplat based chemotherapy on advanced ovarian cancer.

Journal of Postgraduate Medicine

关键词: Antineoplastic Combined Chemotherapy Protocols;    administration &;    dosage;    Cisplatin;    administration &;    dosage;    Comparative Study;    Cyclophosphamide;    administration &;    dosage;    Doxorubicin;    administration &;    dosage;    Female;    Fluorouracil;    administration &;    dosage;    Human;    Methotrexate;    administration &;    dosage;    Ovarian Neoplasms;    drug therapy;    pathology;    surgery;    Survival Rate;    Treatment Outcome;   

DOI  :  

来源: DOAJ

【 摘 要 】

Cisplatinum based chemotherapy has become the standard treatment for ovarian cancers due to its proved superiority over non-cisplat based regimes. However, the therapeutic impact of cisplat based regimes compared to cheaper non-cisplatinum based regimes is questionable when multiple variables such as residual disease, histologic type, grade are introduced. This report is a study of 110 Stage III ovarian cancer patients from 1985-89, with cisplat (n = 69) and non cisplat (n = 41) based chemotherapy. The results of both regimes with reference to the multiple variable factors are presented. We conclude that cisplat based regimes appear to be superior to non-cisplat based regimes except probably in poorly differentiated ovarian tumors where the results were similar with either regimen.

【 授权许可】

Unknown