Functional olfactory evolution in Drosophila suzukii and the subgenus Sophophora

iScience

Jin Zhang¹  Nitin Gupta²  Markus Knaden³  Bill S. Hansson⁴  Heiko Vogel⁴  George F. Obiero⁵  Ian W. Keesey⁵  Abhishek Gupta⁵  Ana Depetris-Chauvin⁵ 

[1] Corresponding author;Department of Biochemistry and Biotechnology, Technical University of Kenya, Haille-Sellasie Avenue, Workshop Rd, 0200 Nairobi, Kenya;Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh 208016, India;Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh 208016, India;Max Planck Institute for Chemical Ecology, Department of Evolutionary Neuroethology, Hans-Knöll-Straße 8, D-07745 Jena, Germany;

关键词: agricultural science;    Entomology;    evolutionary biology;    sensory neuroscience;   

DOI  :  

来源: DOAJ

【 摘 要 】

Summary: Comparative analyses of multiple genomes are used extensively to examine the gains and losses of chemosensory receptors across the genus Drosophila. However, few studies have delved into functional olfactory characteristics. Here we assess olfactory function across 20 species, and identify and describe several similar elements of evolution. We document (a) minor changes in functional ligands based on amino acid substitutions, (b) major changes in olfactory function or perhaps entire receptor replacements, and (c) that only a few receptors are subject to repeated changes, whereas 32 out of 37 OSNs are largely functionally conserved. In addition, we generate a robust model for identifying olfactory function using genomic data and comprehensive ligand-receptor combinations, which includes the prediction of binding pockets. Moreover, this study highlights that functional olfactory evolution does not affect all chemosensory receptors equally, and that ecological, evolutionary, and developmental forces repeatedly affect only a small subset of available receptor proteins.

【 授权许可】

Unknown