Acute adrenaline myocardial necrosis prevention by artificial lung ventilation in experimental settings

Российский кардиологический журнал

V. A. Oganyan¹  A. B. Semerdzhyan¹  S. A. Sisakyan¹  A. S. Sisakyan¹  N. F. Krasnikov¹ 

[1]Ереванский государственный медицинский университет

关键词: catecholamines;    toxic doses;    negative effect;    heart function;    artificial lung ventilation;    positive role;   

DOI  :  

来源: DOAJ

【 摘 要 】

In experimental settings, hystotoxic catecholamine doses depress cardiomyocyte contractility, induce arrhythmia, and heart arrest. Edema and hemorrhages in lung tissue and myocardium, myocardial hemomicrocirculation disturbances, significantly disturbed CO2, O2 partial pressure, and blood pH, plus increased acidosis are observed. Artificial lung ventilation (ALV) prevents fibrillation and heart arrest, edema and generalized lung hemorrhages after lethal catecholamine dose infusion. In addition, ALV prevents hypercapnia, acidosis, and increases blood oxygenation.

【 授权许可】

Unknown