Conversion of Alcohols into Amides Using Alumina-Methanesulfonic Acid (AMA) in Nitrile Solvents

Iranian Journal of Chemistry & Chemical Engineering

Khodabakhsh Niknam¹  Hashem Sharghi¹ 

[1] Department of Chemistry, Shiraz University, Zip code 71454, Shiraz, I.R. IRAN;

关键词: alumina-methanesulfonic acid;    amide;    alcohol;    nitrile;    diamides;    alcohol into amides;    conversion;   

DOI  :  

来源: DOAJ

【 摘 要 】

The reaction of tertiary, secondary and benzylic alcohols with different nitriles in the presence of alumina-methanesulfonic acid (AMA) as a new reagent affords the corresponding amides in good yields (Table 1, 2). Conversion of 2,6-bis(hydroxymethyl)-4-halo anisoles into corresponding diamides in the range of 68-76% yields (Table 3) are also included in this paper.

【 授权许可】

Unknown