Overlapping tumor‐specific expression of p53, p16INK4a, and sirtuin 1 in Bowen's disease: A case report

Clinical Case Reports

Tomoaki Takada¹ 

[1] Sumikawa Takada Dermatology Clinic Sapporo‐shi Japan;

关键词: Bowen's disease;    immunohistochemical stain;    p16INK4a;    p53;    sirtuin 1/SIRT1;   

DOI  :  10.1002/ccr3.3400

来源: DOAJ

【 摘 要 】

Abstract Understanding the impact of inactivating mutations in SIRT1 on the p53 and p16 tumor suppressor genes may yield new insight into the oncogenic mechanisms underlying Bowen's disease.

【 授权许可】

Unknown