A Case of Bacillus Calmette-Guérin Cystitis Diagnosed with a Novel Loop-mediated Isothermal Amplification Method

Urology Case Reports

Takuya Maeda¹  Kazuyoshi Tachi²  Tomohiko Asano²  Akinori Sato²  Akihiko Kawana³  Yuji Kouzaki³ 

[1] Department of Microbiology, Saitama Medical University, Morohongo 38, Moroyama, Iruma-gun, Saitama, Japan;Department of Urology, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan;Division of Infectious Diseases and Pulmonary Medicine, Department of Internal Medicine, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan;

关键词: Bacillus Calmette-Guérin;    Cystitis;    Loop-mediated isothermal amplification;   

DOI  :  10.1016/j.eucr.2017.06.002

来源: DOAJ

【 摘 要 】

Intravesical bacillus Calmette–Guérin (BCG) instillation is broadly used to prevent bladder cancer recurrence or to treat carcinoma in situ. BCG infection is rare but can cause serious problems because this strain has intrinsic resistance to pyrazinamide, a first-line anti-tuberculosis drug. Furthermore, there had been no specific and easy procedure accurately diagnosing BCG infection. In this case report we present the first case of BCG cystitis diagnosed with a newly developed easy-to-use diagnostic procedure using the loop-mediated isothermal amplification method.

【 授权许可】

Unknown