Chemoselective C-benzoylation of phenols by using AlCl3 under solvent-free conditions

Bulletin of the Chemical Society of Ethiopia

关键词: Chemoselective C-acylation;    F-C reaction;    Fries rearrangement;   

DOI  :  http://dx.doi.org/10.4314/bcse.v29i2.14

来源: DOAJ

【 摘 要 】

Substituted phenols were chemo-selectively reacted with benzoylchloride in presence of aluminum chloride under solvent-free condition to afford the corresponding 2'-hydroxy aryl benzophenones in excellent yields (72-96%). Naphthol benzoylation resulted in lower yields as compared to phenols. Both reactions completed in 5-10 min with quantitative yields providing excellent control over regioselectivity of products.

【 授权许可】

Unknown