Applications of bioimpedance measurement techniques in tissue engineering

Journal of Electrical Bioimpedance

Kalvøy H.¹  Amini M.²  Hisdal J.³ 

[1] Department of Clinical and Biomedical Engineering, Rikshospitalet, Oslo University Hospital, Oslo, Norway;Department of Physics, University of Oslo, Oslo, Norway;Vascular Investigations and Circulation lab, Aker Hospital, Oslo University Hospital, Oslo, Norway;

关键词: tissue engineering;    bioimpedance measurement;    non-invasive monitoring;   

DOI  :  10.2478/joeb-2018-0019

来源: DOAJ

【 摘 要 】

Rapid development in the field of tissue engineering necessitates implementation of monitoring methods for evaluation of the viability and characteristics of the cell cultures in a real-time, non-invasive and non-destructive manner. Current monitoring techniques are mainly histological and require labeling and involve destructive tests to characterize cell cultures. Bioimpedance measurement technique which benefits from measurement of electrical properties of the biological tissues, offers a non-invasive, label-free and real-time solution for monitoring tissue engineered constructs. This review outlines the fundamentals of bioimpedance, as well as electrical properties of the biological tissues, different types of cell culture constructs and possible electrode configuration set ups for performing bioimpedance measurements on these cell cultures. In addition, various bioimpedance measurement techniques and their applications in the field of tissue engineering are discussed.

【 授权许可】

Unknown