Untangling Photofaradaic and Photocapacitive Effects in Organic Optoelectronic Stimulation Devices

Frontiers in Bioengineering and Biotechnology

Vedran Ðerek¹  Eric Daniel Głowacki³  Yael Hanein⁵  David Rand⁵  Ludovico Migliaccio⁶ 

[1] Center of Excellence for Advanced Materials and Sensing Devices, Ruđer Bošković Institute, Zagreb, Croatia;Department of Physics, Faculty of Science, University of Zagreb, Zagreb, Croatia;Faculty of Chemistry, Warsaw University of Technology, Warsaw, Poland;Laboratory of Organic Electronics, Campus Norrköping, Linköping University, Norrköping, Sweden;Tel Aviv University Center for Nanoscience and Nanotechnology, School of Electrical Engineering Tel Aviv University, Tel Aviv, Israel;Wallenberg Centre for Molecular Medicine, Linköping University, Linköping, Sweden;

关键词: bioelectronics;    neurostimulation;    organic electronics;    photoelectrochemistry;    photostimulation;   

DOI  :  10.3389/fbioe.2020.00284

来源: DOAJ

【 摘 要 】

Light, as a versatile and non-invasive means to elicit a physiological response, offers solutions to problems in basic research as well as in biomedical technologies. The complexity and limitations of optogenetic methods motivate research and development of optoelectronic alternatives. A recently growing subset of approaches relies on organic semiconductors as the active light absorber. Organic semiconductors stand out due to their high optical absorbance coefficients, mechanical flexibility, ability to operate in a wet environment, and potential biocompatibility. They could enable ultrathin and minimally invasive form factors not accessible with traditional inorganic materials. Organic semiconductors, upon photoexcitation in an aqueous medium, can transduce light into (1) photothermal heating, (2) photochemical/photocatalytic redox reactions, (3) photocapacitive charging of electrolytic double layers, and (4) photofaradaic reactions. In realistic conditions, different effects may coexist, and understanding their role in observed physiological phenomena is an area of critical interest. This article serves to evaluate the emerging picture of photofaradaic vs. photocapacitive effects in the context of our group’s research efforts and that of others over the past few years. We present simple experiments which can be used to benchmark organic optoelectronic stimulation devices.

【 授权许可】

Unknown