5-Florourasil ve folinik asit tedavisi alan kolon karsinomlu olguda tedavi sonrasi skleroderma

Çukurova Üniversitesi Tıp Fakültesi Dergisi

Ozgur Ozyilkan¹  Ahmet Eftal Yuce²  Didem Arslan Tas³ 

[1] Baskent Universitesi, Tip Fakultesi, Medikal OnkolojiBD;Baskent Universitesi, Tip Fakultesi, Romatoloji BD;Cukurova Universitesi, Tip Fakultesi, Romatoloji-Immunoloji BD;

关键词: Scleroderma;    colon cancer;    5 fluorouracil;   

DOI  :  

来源: DOAJ

【 摘 要 】

Sistemic sclerosis is a connective tissue disease which is characterized by the increase amount of collagene in subcutaneous tissue and internal organs. Several chemical agents and environmental factors are accused fort he etiopathogenesis however the etiology is not clear. There is limited data abput the increased frequency of colon carcinoma in the cases with sistemic sclerosis. There are 2 cases in the literature about the association between scleroderma and 5-fluorouracil which is used for the treatment of colon carcinoma. Similar clinical course and autoantibody positivity was also reported in a patient with tymic carcinoma who had been treated with 5-FU and folinic acid. In this article, a 51-year-old woman who developed scleroderma after 5-FU and folinic acid therapy which had been started for colon carcinoma has been reported. [Cukurova Med J 2014; 39(2.000): 362-364]

【 授权许可】

Unknown