Extranodal NK/T-Cell Lymphomas: The Role of Natural Killer Cells and EBV in Lymphomagenesis

International Journal of Molecular Sciences

Atif Saleem¹  Yasodha Natkunam¹ 

[1] Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA;

关键词: nk cells;    extranodal nk/t-cell lymphoma;    ebv;   

DOI  :  10.3390/ijms21041501

来源: DOAJ

【 摘 要 】

Natural killer (NK) cells are lymphocytes involved in innate and adaptive immune functions. They are the presumed cell of origin of distinct hematolymphoid malignancies, including aggressive NK-cell leukemia and extranodal NK/T-cell lymphoma (ENKTL). This review focuses on the role of NK cells and Epstein−Barr virus (EBV) in ENKTL pathogenesis.

【 授权许可】

Unknown