Hyper-reactive Malarial Splenomegaly (HMS) in a patient with ,'' thalassaemia syndrome

The Pan African Medical Journal

George Bedu-Addo¹  Yaw Ampem Amoako¹ 

[1] Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana;

关键词: hyper-reactive malarial splenomegaly;    béta thalassemia syndrome;    proguanil;    massive splenomegaly;    ghana;   

DOI  :  10.11604/pamj.2014.19.310.5576

来源: DOAJ

【 摘 要 】

This report describes a case of hyper-reactive malarial splenomegaly in a patient with a thalassaemia syndrome. Increased haemoglobin A2 is valuable for the diagnosis of common forms of ''-thalassemia, while haemoglobin F (HbF) helps in diagnosis of the rarer - forms. Thalassemia is characterised by splenomegaly and is common in malaria endemic areas. Hyper-reactive malarial splenomegaly is also a common cause of massive splenomegaly in malaria endemic areas. Splenic enlargement regresses with prolonged antimalarial therapy.

【 授权许可】

Unknown