Synthesis of aromatic lactone analogues of Lipoxin A4

BMC Research Notes

Muhammad Zeeshan¹  Jørn H. Hansen¹  Aya Ismael¹ 

[1] Department of Chemistry, Chemical Synthesis and Analysis Division, UiT The Arctic University of Norway;

关键词: Lipoxin analogues;    Aromatics;    Wittig olefination;    Lactones;   

DOI  :  10.1186/s13104-022-05917-4

来源: DOAJ

【 摘 要 】

Abstract Objective Synthesis of novel aromatic Lipoxin A4 lactone analogues. Results Novel para-substituted aromatic lactone analogues of Lipoxin A4 have been synthesized in a convergent manner with six steps in the longest linear sequence in 12–13% yields, employing 2-deoxy-d-ribose as a chiral pool starting material and the classical E-selective Wittig olefination.

【 授权许可】

Unknown