A community perspective on the concept of marine holobionts: current status, challenges, and future directions

PeerJ

Fabrice Not¹  François H. Lallier¹  Mahasweta Saha²  Aschwin H. Engelen³  Alexey Vorobev⁴  Mónica Medina⁵  Shinichi Sunagawa⁶  Ezequiel M. Marzinelli⁷  Ehsan Kayal⁸  Enrique Arboleda⁸  Eve Toulza⁹  Elena Kazamia^1,10  Arite Bigalke^1,11  José Pintado^1,12  Catherine Leblanc^1,13  Simon M. Dittami^1,13  Ulisse Cardini^1,14  Enora Briand^1,15  Johan Decelle^1,16  Damien Eveillard^1,17  Willem Stock^1,18  Jean-Christophe Auguet^1,19  Teresa Maria Morganti^2,20  Soizic Prado^2,21  Marc-André Selosse^2,22  Paco Cárdenas^2,23  Derek Skillings^2,24  Sarah M. Griffiths^2,25  Claire M.M. Gachon^2,26  Laura Núñez Pons^2,27  Tilmann Harder^2,28 

[1]Adaptation and Diversity in the Marine Environment, Station Biologique de Roscoff, Sorbonne Université, CNRS, Roscoff, France

[2]Benthic Ecology, Helmholtz Center for Ocean Research, Kiel, Germany

[3]CCMAR, Universidade do Algarve, Faro, Portugal

[4]CEA - Institut de Biologie François Jacob, Genoscope, Evry, France

[5]Department of Biology, Pennsylvania State University, University Park, United States of America

[6]Dept. of Biology, Institute of Microbiology and Swiss Institute of Bioinformatics, ETH, Zürich, Switzerland

[7]Ecology and Environment Research Centre, The University of Sydney, Sydney, Australia

[8]FR2424, Station Biologique de Roscoff, Sorbonne Université, CNRS, Roscoff, France

[9]IHPE, Univ. de Montpellier, CNRS, IFREMER, UPDV, Perpignan, France

[10]Institut de Biologie, ENS, Paris, France

[11]Institute for Inorganic and Analytical Chemistry, Bioorganic Analytics, Friedrich-Schiller-Universität Jena, Jena, Germany

[12]Instituto de Investigaciones Marinas, CSIC, Vigo, Spain

[13]Integrative Biology of Marine Models (LBI2M), Station Biologique de Roscoff, Sorbonne Université, CNRS, Roscoff, France

[14]Integrative Marine Ecology Dept, Stazione Zoologica Anton Dohrn, Napoli, Italy

[15]Laboratoire Phycotoxines, Ifremer, Nantes, France

[16]Laboratoire de Physiologie Cellulaire et Végétale, Université Grenoble Alpes, CNRS, CEA, INRA, Grenoble, France

[17]Laboratoire des Sciences Numériques de Nantes (LS2N), Université de Nantes, CNRS, Nantes, France

[18]Laboratory of Protistology & Aquatic Ecology, Department of Biology, Ghent University, Ghent, Belgium

[19]MARBEC, Université de Montpellier, CNRS, IFREMER, IRD, Montpellier, France

[20]Max Planck Institute for Marine Microbiology, Bremen, Germany

[21]Molecules of Communication and Adaptation of Microorganisms (UMR 7245), National Museum of Natural History, CNRS, Paris, France

[22]National Museum of Natural History, Département Systématique et Evolution, Paris, France

[23]Pharmacognosy, Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden

[24]Philosophy Department, University of Pennsylvania, Philadelphia, United States of America

[25]School of Science and the Environment, Manchester Metropolitan University, Manchester, United Kingdom

[26]Scottish Marine Institute, Scottish Association for Marine Science, Oban, United Kingdom

[27]Section Biology and Evolution of Marine Organisms, Stazione Zoologica Anton Dohrn, Napoli, Italy

[28]University of Bremen, Bremen, Germany

关键词: Evolution;    Ecosystem services;    Symbiosis;    Host-microbiota interactions;    Marine holobionts;    Dysbiosis;   

DOI  :  10.7717/peerj.10911

来源: DOAJ

【 摘 要 】

Host-microbe interactions play crucial roles in marine ecosystems. However, we still have very little understanding of the mechanisms that govern these relationships, the evolutionary processes that shape them, and their ecological consequences. The holobiont concept is a renewed paradigm in biology that can help to describe and understand these complex systems. It posits that a host and its associated microbiota with which it interacts, form a holobiont, and have to be studied together as a coherent biological and functional unit to understand its biology, ecology, and evolution. Here we discuss critical concepts and opportunities in marine holobiont research and identify key challenges in the field. We highlight the potential economic, sociological, and environmental impacts of the holobiont concept in marine biological, evolutionary, and environmental sciences. Given the connectivity and the unexplored biodiversity specific to marine ecosystems, a deeper understanding of such complex systems requires further technological and conceptual advances, e.g., the development of controlled experimental model systems for holobionts from all major lineages and the modeling of (info)chemical-mediated interactions between organisms. Here we propose that one significant challenge is to bridge cross-disciplinary research on tractable model systems in order to address key ecological and evolutionary questions. This first step is crucial to decipher the main drivers of the dynamics and evolution of holobionts and to account for the holobiont concept in applied areas, such as the conservation, management, and exploitation of marine ecosystems and resources, where practical solutions to predict and mitigate the impact of human activities are more important than ever.

【 授权许可】

Unknown