An Updated Review of Ciguatera Fish Poisoning: Clinical, Epidemiological, Environmental, and Public Health Management

Marine Drugs

Matthew O. Gribble¹  Danielle Clarkson-Townsend¹  Ram Ayyar²  Mercedes Fernandez³  Lora E. Fleming⁴  Richard Weisman⁵  Wendy Stephan⁵  Karen Swajian⁶  Stacey Degrasse⁶  Christopher R. Loeffler⁷  Harold A. Flores Quintana⁷  Ronald Benner⁷  Elisa Berdalet⁸  Jeffrey Bernstein⁹  Kathleen Schrank⁹  Robert W. Dickey^1,10  Melissa A. Friedman^1,11  Steven Kibler^1,12  Lorraine C. Backer^1,13  Tom Brewer^1,14  Paul Bienfang^1,15  Donna Blythe^1,16  Robert E. Bowen^1,17 

[1] Department of Environmental Health, Emory University Rollins School of Public Health, Atlanta, GA 30322, USA;Department of Neurology, University of Miami, Miami, FL 33136, USA;Department of Psychology and Neuroscience, Nova Southeastern University, Fort Lauderdale, FL 33314, USA;European Centre for Environment and Human Health, University of Exeter Medical School, Truro, Cornwall Tr1 3HD, UK;Florida Poison Information Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA;Food and Drug Administration, College Park, MD 20740, USA;Food and Drug Administration, Dauphin Island, AL 36528, USA;Institut de Ciències del Mar (CSIC), 08003 Barcelona, Spain;Jackson Memorial Medical Center, Department of Medicine, University of Miami, Miami, FL 33136, USA;Marine Science Institute, University of Texas at Austin, Port Aransas, TX 78373, USA;Mount Sinai Medical Center, Miami Beach, FL 33140, USA;NOAA-National Ocean Service, Center for Coastal Fisheries and Habitat Research, Beaufort, NC 28516, USA;National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA;Northern Institute, Charles Darwin University, Darwin 0909, Australia and Australian Institute of Marine Science, Darwin 0811, Australia;Oceanography Department, University of Hawaii, Honolulu, HI 96822, USA;Private Practice, Miami, FL 33133, USA;School for the Environment, University of Massachusetts Boston, Boston, MA 02125, USA;

关键词: ciguatera fish poisoning;    ciguatoxin;    harmful algal bloom;    algae;    seafood poisoning;    Gambierdiscus;    diagnosis;    treatment;    human health;    natural toxins;    climate change;    environmental change;    food poisoning;    neuropsychology;    neurology;    neurotoxin;   

DOI  :  10.3390/md15030072

来源: DOAJ

【 摘 要 】

Ciguatera Fish Poisoning (CFP) is the most frequently reported seafood-toxin illness in the world. It causes substantial human health, social, and economic impacts. The illness produces a complex array of gastrointestinal, neurological and neuropsychological, and cardiovascular symptoms, which may last days, weeks, or months. This paper is a general review of CFP including the human health effects of exposure to ciguatoxins (CTXs), diagnosis, human pathophysiology of CFP, treatment, detection of CTXs in fish, epidemiology of the illness, global dimensions, prevention, future directions, and recommendations for clinicians and patients. It updates and expands upon the previous review of CFP published by Friedman et al. (2008) and addresses new insights and relevant emerging global themes such as climate and environmental change, international market issues, and socioeconomic impacts of CFP. It also provides a proposed universal case definition for CFP designed to account for the variability in symptom presentation across different geographic regions. Information that is important but unchanged since the previous review has been reiterated. This article is intended for a broad audience, including resource and fishery managers, commercial and recreational fishers, public health officials, medical professionals, and other interested parties.

【 授权许可】

Unknown