Carbonic Anhydrase Inhibitors in the Treatment of Glaucoma. Review. Part II

Oftalʹmologiâ

N. I. Kurysheva¹ 

[1] The Department of Eye Diseases at the Medical Biological University of Innovations and Continuing Education of the A.I. Burnasyan Federal Medical Biophysical Center of the Federal Medical Biological Agency (FMBA);

关键词: carbonic anhydrase inhibitors;    glaucoma;    side effects;    pregnancy;    antioxidant activity;    aqueous humor;    multipurpose glaucoma treatment strategy;   

DOI  :  10.18008/1816-5095-2020-4-676-682

来源: DOAJ

【 摘 要 】

Topical and systemic carbonic anhydrase inhibitors (CAIs) are widely used in the treatment of glaucoma for reducing intraocular pressure. This part of the review describes the characteristics of systemic CAIs, their side effects and the ways to overcome them, as well as contraindications. The use of CAIs during pregnancy is considered. Particular attention is paid to the antioxidant activity of CAIs and the promising development of hybrid forms based on the existing CAIs as a part of a multipurpose glaucoma treatment strategy.

【 授权许可】

Unknown