PREVALENCE OF MARKERS OF ENTERAL VIRAL HEPATITIS AMONG MIGRANT WORKERS ARRIVING IN RUSSIAN FEDERATION

Журнал микробиологии, эпидемиологии и иммунобиологии

D. A. Sychev¹  K. K. Kyuregyan²  I. A. Potemkin²  M. I. Mikhaylov³  S. D. Alsalikh⁴ 

[1] Centre of Hygiene and Epidemiology in Moscow Region;Mechnikov Research Institute of Vaccines and Sera, Russian Medical Academy of Continuous Professional Education;Russian University of Peoples’ Friendship, Mechnikov Research Institute of Vaccines and Sera, Russian Medical Academy of Continuous Professional Education;Russian University of Peoples’ Friendship;

关键词: hepatitis a;    hepatitis e;    trade migrants;    viral hepatitis markers;   

DOI  :  10.36233/0372-9311-2017-3-59-64

来源: DOAJ

【 摘 要 】

Aim. Determination of prevalence of markers of hepatitis A and E among migrant workers, who had recently arrived in Russian Federation from countries with various degree of endemicity regarding this infection. Materials and methods. Sera samples from 1333 migrant workers, who had recently arrived in Russian Federation from Uzbekistan (n=464), Tadzhikistan (n=415), Ukraine |n=308) and Moldova (n=146) were studied. Anti-HAV IgG, anti-HEV IgM and IgG were determined using commercial ELISA tests. HEV RNA was determined in samples positive for anti-HEV IgM by RT-PCR with degenerate primers to HEV genome sequence coding capsid protein. Anti-HEV IgG were detected significantly more frequently among migrants from Uzbekistan and Tajikistan compared with migrants from the Ukraine and Moldova (25,4 and 43,1% versus 7,8 and 12,3%, respectively, p

【 授权许可】

Unknown