Berberis vulgaris alleviates Levodopa-induced dyskinesia in male mice

Herba Polonica

Mokarian Faezeh¹  Jahromy Mahsa Hadipour¹  Famitafreshi Hamidreza² 

[1] Herbal Pharmacology Research Center, Department of Pharmacology, Faculty of Medicine, Tehran Medical Sciences, Islamic Azad UniversityTehran, Iran;Physiology Department, Faculty of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran;

关键词: Parkinson’s disease;    Levodopa induced dyskinesia;    Berberis vulgaris;    dyskinesia;    cylinder test;    AIMS test;   

DOI  :  10.2478/hepo-2018-0023

来源: DOAJ

【 摘 要 】

Introduction: Parkinson’s disease is a chronic debilitating disease and many patients use Levodopa as a major treatment. However, this drug in long-term use causes a serious condition that is known as Levodopa-induced dyskinesia (LID). Berberis vulgaris (BV) has been known to be a good potential medication for neurologic diseases such as movement disorders. The aim of this study is to investigate the usefulness of BV for LID in mice.

【 授权许可】

Unknown