Role of Anterior Segment-Optical Coherence Tomography Angiography in Acute Ocular Burns

Diagnostics

Sayan Basu¹  Anahita Kate² 

[1] The Cornea Institute, Kallam Anji Reddy Campus, LV Prasad Eye Institute, Hyderabad 500034, India;The Cornea Institute, Kode Venkatadri Chowdary Campus, LV Prasad Eye Institute, Vijayawada 521134, India;

关键词: acute ocular burns;    ocular chemical burns;    eye burns;    limbal ischemia;    optical coherence tomography;    angiography;   

DOI  :  10.3390/diagnostics12030607

来源: DOAJ

【 摘 要 】

Acute ocular burns have varied manifestations which require prompt diagnosis and management to prevent chronic sequelae. Of these, the detection of limbal ischemia poses a challenge because of the subjective nature of its clinical signs. Anterior segment optical coherence tomography angiography (AS-OCTA) offers an objective method of assessing ischemia in these eyes. This review provides an overview of the technology of AS-OCTA and its applications in acute burns. AS-OCTA generates images by isolating the movement of erythrocytes within blood vessels from sequentially obtained b-scans. Limbal ischemia manifests in these scans as absent vasculature and the extent of ischemia can be quantified using different vessel-related parameters. Of these, the density of vessels is most commonly used and correlates with the severity of the injury. Incorporation of the degree of ischemia in the classification of acute burns has been attempted in animal studies and its extension to human trials may provide an added dimension in determining the final prognosis of these eyes. Thus, AS-OCTA is a promising device that can objectively evaluate limbal ischemia. This will facilitate the identification of patients who will benefit from revascularization therapies and stem cell transplants in acute and chronic ocular burns, respectively.

【 授权许可】

Unknown