Opsin1 regulates light-evoked avoidance behavior in Aedes albopictus

BMC Biology

Xinyi Liu¹  Si Wu¹  Zongzhao Zhai¹  Shuzhen Yang¹  Yuan Yao¹  Pa Wu¹ 

[1] Hunan Provincial Key Laboratory of Animal Intestinal Function and Regulation, Hunan International Joint Laboratory of Animal Intestinal Ecology and Health, College of Life Sciences, Hunan Normal University;

关键词: Opsin1;    Aedes albopictus;    Aedes aegypti;    Culex quinquefasciatus;    Photobehavior;    Vision;   

DOI  :  10.1186/s12915-022-01308-0

来源: DOAJ

【 摘 要 】

Abstract Background Mosquitoes locate a human host by integrating various sensory cues including odor, thermo, and vision. However, their innate light preference and its genetic basis that may predict the spatial distribution of mosquitoes, a prerequisite to encounter a potential host and initiate host-seeking behaviors, remains elusive. Results Here, we first studied mosquito visual features and surprisingly uncovered that both diurnal (Aedes aegypti and Aedes albopictus) and nocturnal (Culex quinquefasciatus) mosquitoes significantly avoided stronger light when given choices. With consistent results from multiple assays, we found that such negative phototaxis maintained throughout development to adult stages. Notably, female mosquitoes significantly preferred to bite hosts in a shaded versus illuminated area. Furthermore, silencing Opsin1, a G protein-coupled receptor that is most enriched in compound eyes, abolished light-evoked avoidance behavior of Aedes albopictus and attenuated photonegative behavior in Aedes aegypti. Finally, we found that field-collected Aedes albopictus also prefers darker area in an Opsin1-dependent manner. Conclusions This study reveals that mosquitoes consistently prefer darker environment and identifies the first example of a visual molecule that modulates mosquito photobehavior.

【 授权许可】

Unknown