Cross-Sectional Study on the Prevalence of PCV Types 2 and 3 DNA in Suckling Piglets Compared to Grow–Finish Pigs in Downstream Production

Pathogens

Roman Krejci¹  Vojislav Cvjetković²  Roland Maurer³  Mathias Ritzmann³  Matthias Eddicks³  Pauline Deffner³  Wolfgang Sipos⁴  Robert Fux⁵  Sven Reese⁶  Lina Eddicks⁷  Tanja Opriessnig⁸ 

[1] Ceva Santé Animale, 33500 Libourne, France;Ceva Tiergesundheit GmbH, 40472 Duesseldorf, Germany;Clinic for Swine at the Centre for Clinical Veterinary Medicine, Ludwig-Maximilians-Universität München, 85764 Oberschleissheim, Germany;Clinical Department for Farm Animals and Herd Management, University of Veterinary Medicine Vienna, 1210 Vienna, Austria;Division of Virology, Department of Veterinary Sciences, Ludwig-Maximilians-Universität München, 80539 Munich, Germany;Institute for Anatomy, Histology and Embryology, Ludwig-Maximilians-Universität München, 80539 Munich, Germany;Institute of Veterinary Pathology at the Centre for Clinical Veterinary Medicine, Ludwig-Maximilians-Universität München, 80539 Munich, Germany;The Roslin Institute and The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK;

关键词: porcine circoviruses;    oral fluids;    suckling piglets;    tissue samples;   

DOI  :  10.3390/pathogens11060671

来源: DOAJ

【 摘 要 】

Vertical transmission is a consistently discussed pathway of porcine circovirus type 2 (PCV2) and porcine circovirus type 3 (PCV3) transmission in pigs. To evaluate the presence of PCV2 and PCV3 in piglets, we collected tissue samples from 185 piglets that were crushed within the first week of life from 16 farms located in Germany and Austria. Pooled samples consisting of thymus, inguinal lymph node, myocardium, lung and spleen were examined for PCV2 and PCV3 by qPCR. Furthermore, oral fluid samples (OFS) from grow–finish pigs were collected and examined the same way. In piglets, PCV2 was highly prevalent (litters: 69.4%; piglets: 61.6%), whereas PCV3 prevalence was low (litters: 13.4%; piglets: 13.0%). In total, 72.6% and 67.2% of all collected OFS were PCV2 or PCV3 positive, respectively. Sow vaccination against PCV2 was identified as a protective factor concerning PCV2 in piglets (OR: 0.279; CI: 0.134–0.578; p < 0.001), whereas the porcine reproductive and respiratory syndrome virus (PRRSV) vaccination of sows was identified as a protective factor concerning PCV3 in piglets (OR: 0.252 CI: 0.104–0.610; p = 0.002). Our results show that PCV2, but not PCV3, is ubiquitous in suckling piglets and that early PCV3 infections might be modulated by PRRSV–PCV3 interaction. However, the ubiquitous nature of both viruses in older pigs could be confirmed.

【 授权许可】

Unknown