BK polyomavirus-associated nephropathy

Childhood Kidney Diseases

Hee Gyung Kang¹  Yo Han Ahn¹ 

[1] Department of Pediatrics, Seoul National University College of Medicine, Seoul, Republic of Korea;

关键词: bk virus;    immunosuppression therapy;    kidney transplantation;   

DOI  :  10.3339/ckd.22.029

来源: DOAJ

【 摘 要 】

BK polyomavirus (BKPyV) is a ubiquitous virus residing in the kidney tubules and is clinically significant only in immunocompromised patients. In clinical practice, BKPyV is a causative pathogen of BKPyV-associated nephropathy (BKVAN) in kidney allograft recipients or hemorrhagic cystitis of hematopoietic stem cell transplant recipients. Currently, there is no effective treatment for BKVAN; therefore, careful monitoring and prudent modification of immunosuppression are necessary to prevent BKVAN. In this article, the epidemiology, pathophysiology, and current management strategies for BKVAN are reviewed.

【 授权许可】

Unknown