Multifocal tuberculosis-associated immune reconstitution inflammatory syndrome – a case report of a complicated scenario

BMC Infectious Diseases

Narayanan Ravichandran¹  Kesavamurthy Banu²  Caian L. Vinhaes³  Kiyoshi F. Fukutani³  Kevan Akrami³  Bruno B. Andrade³  Deivide Oliveira-de-Souza³  Gopalan Narendran⁴  Soumya Swaminathan⁴  Padmapriyadarsini Chandrasekaran⁴  Irini Sereti⁵ 

[1] Government Hospital of Thoracic Medicine;Institute of Neurology, Madras Medical College;Instituto GonçaloMoniz, Fundação Oswaldo Cruz;National Institute for Research in Tuberculosis;National Institutes of Allergy and Infectious Diseases, National Institutes of Health;

关键词: Immune reconstitution inflammatory syndrome;    IRIS;    Tuberculosis;    HIV;   

DOI  :  10.1186/s12879-019-4182-1

来源: DOAJ

【 摘 要 】

Abstract Background Tuberculosis (TB)-associated Immune reconstitution inflammatory syndrome (TB-IRIS) is an aberrant inflammatory response in TB patients with advanced human immunodeficiency virus coinfection, after antiretroviral therapy commencement. Case presentation We present a rare case of a 51-year-old woman living with HIV who developed a series of TB-IRIS events occurring at multiple sites sequentially, highlighting the clinical complexity in diagnosis and management. Conclusion This case illustrates how complicated a clinical scenario of successive TB-IRIS episodes can be, in terms of clinical management.

【 授权许可】

Unknown