A Life Cycle for Modeling Biology at Different Scales

Frontiers in Plant Science

Chelsea D. Specht¹  Jesús Martínez-Gómez¹  Kate Harline³  Adrienne H. K. Roeder³ 

[1] L.H. Bailey Hortorium, Cornell University, Ithaca, NY, United States;Section of Plant Biology, School of Integrative Plant Science, Cornell University, Ithaca, NY, United States;Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY, United States;

关键词: evo-devo;    biomechanics;    morphodynamics;    developmental modeling;    plant morphogenesis;   

DOI  :  10.3389/fpls.2021.710590

来源: DOAJ

【 摘 要 】

Modeling has become a popular tool for inquiry and discovery across biological disciplines. Models allow biologists to probe complex questions and to guide experimentation. Modeling literacy among biologists, however, has not always kept pace with the rise in popularity of these techniques and the relevant advances in modeling theory. The result is a lack of understanding that inhibits communication and ultimately, progress in data gathering and analysis. In an effort to help bridge this gap, we present a blueprint that will empower biologists to interrogate and apply models in their field. We demonstrate the applicability of this blueprint in two case studies from distinct subdisciplines of biology; developmental-biomechanics and evolutionary biology. The models used in these fields vary from summarizing dynamical mechanisms to making statistical inferences, demonstrating the breadth of the utility of models to explore biological phenomena.

【 授权许可】

Unknown