Smartphone microendoscopy for high resolution fluorescence imaging

Journal of Innovative Optical Health Sciences

Xiangqian Hong¹  Dale H. Mugler¹  Vivek K. Nagarajan¹  Bing Yu¹ 

[1] Department of Biomedical Engineering, The University of Akron, Akron, Ohio 44325, USA;

关键词: Endoscopy;    imaging systems;    fluorescence;    fiber optics;   

DOI  :  10.1142/S1793545816500462

来源: DOAJ

【 摘 要 】

High resolution optical endoscopes are increasingly used in diagnosis of various medical conditions of internal organs, such as the cervix and gastrointestinal (GI) tracts, but they are too expensive for use in resource-poor settings. On the other hand, smartphones with high resolution cameras and Internet access have become more affordable, enabling them to diffuse into most rural areas and developing countries in the past decade. In this paper, we describe a smartphone microendoscope that can take fluorescence images with a spatial resolution of 3.1 μm. Images collected from ex vivo, in vitro and in vivo samples using the device are also presented. The compact and cost-effective smartphone microendoscope may be envisaged as a powerful tool for detecting pre-cancerous lesions of internal organs in low and middle-income countries (LMICs).

【 授权许可】

Unknown