Dual-stage 18F-fluorocholine PET/CT scanning for biochemical recurrences of prostate cancer

Onkourologiâ

D. I. Nevzorov¹  A. A. Odzharova¹  S. V. Shiryaev¹  A. I. Mikhailov²  P. E. Tulin²  M. B. Dolgushin²  V. B. Matveev³ 

[1] 23, Kashirskoe Shosse, Moscow 115478, Russia;Department of Positron Emission Tomography N.N. Blokhin Russian Cancer Research Center;Depatment of Radionuclide Diagnosis and Radionuclide Therapy N.N. Blokhin Russian Cancer Research Center;

关键词: pet/ct;    two-staged;    prostate cancer;    18f-fluorocholine;    choline;    biochemical recurrence;    prostatectomy;   

DOI  :  10.17650/1726-9776-2015-11-2-46-54

来源: DOAJ

【 摘 要 】

PET/CT with 18F-fluorocholine, based on an assessment of phosphatidylcholine biodistribution, is an effective method in the diagnosis of biochemical recurrence of prostate cancer. According to results of our study on 71 patients (PSA level 1,775 (0.0245, 56.0975) ng/mL), the sensitivity of two-stage PET/CT with 18F-fluorocholine was 66.7 % (CI 55.3–78 0 %), and specificity – 80 % (CI 44.9–100.0 %), the overall accuracy of the method ranged from 56.7 to 78.5 %. The results show the feasibility of two-staged PET/CT with 18F-fluorocholine in biochemical recurrence of prostate cancer.

【 授权许可】

Unknown