EVEROLIMUS IN DE NOVO RENAL TRANSPLANT RECIPIENTS

Vestnik Transplantologii i Iskusstvennyh Organov

E. I. Prokopenko¹ 

[1] M.F. Vladimirsky Moscow regional clinical research institute, Moscow;

关键词: renal transplantation;    calcineurin inhibitor toxicity;    proliferation signal inhibitors;    everolimus;   

DOI  :  10.15825/1995-1191-2010-2-74-81

来源: DOAJ

【 摘 要 】

Survival of renal transplants and renal transplants recipients has improved greatly last years, but long-term graft survival remains unchanged. Nephrotoxicity of calcineurin inhibitors is one of the main factors of late renal allograft disfunction. Everolimus, new proliferation signal inhibitor, can facilitate minimization cyclosporine A exposure and has antineoplastic activity. The paper reviews literature dates regarding to clinical aspects of everolimus use in de novo renal transplant recipients.

【 授权许可】

Unknown