Vestibular-Evoked Myogenic Potentials in Bilateral Vestibulopathy

Frontiers in Neurology

Sally M. Rosengren²  Miriam S. Welgampola³  Rachael L. Taylor⁵ 

[1] Audiology Department, Whangarei Hospital, Whangarei, New Zealand;Central Clinical School, University of Sydney, Sydney, NSW, Australia;Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, Sydney, NSW, Australia;Neurology Department, Royal Prince Alfred Hospital, Sydney, NSW, Australia;New Zealand Dizziness and Balance Centre, Auckland, New Zealand;

关键词: vestibular-evoked myogenic potential;    otolith;    gentamicin;    aminoglycoside;    bilateral vestibulopathy;    Meniere’s disease;   

DOI  :  10.3389/fneur.2018.00252

来源: DOAJ

【 摘 要 】

Bilateral vestibulopathy (BVP) is a chronic condition in which patients have a reduction or absence of vestibular function in both ears. BVP is characterized by bilateral reduction of horizontal canal responses; however, there is increasing evidence that otolith function can also be affected. Cervical and ocular vestibular-evoked myogenic potentials (cVEMPs/oVEMPs) are relatively new tests of otolith function that can be used to test the saccule and utricle of both ears independently. Studies to date show that cVEMPs and oVEMPs are often small or absent in BVP but are in the normal range in a significant proportion of patients. The variability in otolith function is partly due to the heterogeneous nature of BVP but is also due to false negative and positive responses that occur because of the large range of normal VEMP amplitudes. Due to their variability, VEMPs are not part of the diagnosis of BVP; however, they are helpful complementary tests that can provide information about the extent of disease within the labyrinth. This article is a review of the use of VEMPs in BVP, summarizing the available data on VEMP abnormalities in patients and discussing the limitations of VEMPs in diagnosing bilateral loss of otolith function.

【 授权许可】

Unknown