Isoquinolone Syntheses by Annulation Protocols

Catalysts

Ruimao Hua¹ 

[1] Key Laboratory of Organic Optoelectronics & Molecular, Department of Chemistry, Tsinghua University, Engineering of Ministry of Education, Beijing 100084, China;

关键词: alkyne;    annulation;    isoquinolone;    polycyclic-fused isoquinolone;   

DOI  :  10.3390/catal11050620

来源: DOAJ

【 摘 要 】

Isoquinolones (isoquinolin-1(2H)-ones) are one of the important nitrogen-heterocyclic compounds having versatile biological and physiological activities, and their synthetic methods have been recently developed greatly. This short review illustrates the significant advances in the construction of isoquinolone ring with atom- and step-economy, focusing on the intermolecular annulation protocols and intramolecular cyclization in the presence of a variety of catalyst systems. The syntheses of isoquinolone-fused rings are also included.

【 授权许可】

Unknown