The International Guideline Evaluation Screening Tool (IGEST): development and validation

BMC Medical Research Methodology

Daniela Coclite¹  Antonello Napoletano¹  Alice Josephine Fauci¹  Primiano Iannone¹  Daniela D’angelo¹  Roberto Latina²  Laura Iacorossi³  Greta Castellini⁴  Silvia Gianola⁴ 

[1] National Center for Clinical Excellence, Healthcare Quality and Safety, Istituto Superiore di Sanità;PROMISE Department, University of Palermo;Regina Elena National Cancer Institute;Unit of Clinical Epidemiology, IRCCS Istituto Ortopedico Galeazzi;

关键词: Clinical guideline;    Assessment;    Development;    Validity;    Tool;   

DOI  :  10.1186/s12874-022-01618-5

来源: DOAJ

【 摘 要 】

Abstract Background Guideline adaptation provides an important alternative to de novo guideline development by making the process more efficient and reducing unnecessary duplication. The quality evaluation of international guidelines is an essential part of the adaptation process. The study aims at describing the development and validation of a new tool to screen trustworthy Clinical Practice Guidelines (CPGs) for their adoption/adaption: the International Guideline Evaluation Screening Tool (IGEST). Methods The process of developing the IGEST involved two main phases: 1) tool development and 2) content validation. The tool development phase comprised three stages, where the scope of the IGEST was defined and the item pool was generated and refined. The content validation was performed through the computation of a content validity index (CVI) based on the opinions of an expert panel. Results All the items obtained a CVI >0.78, which resulted in the validation of the instrument. The final instrument comprised four preliminary conditions and 12 criteria organised into three dimensions: (i) the management of conflict of interest; (ii) the quality of evidence and the coherence between evidence and recommendations; and (iii) the panel composition. Conclusion The IGEST showed good content validity for assessing the quality of international guidelines. Using the new tool to select trustworthy guidelines might increase the likelihood that international clinical practice guidelines will be adopted/adapted to the local context by allowing a quick screening of existing guidelines trustworthiness and providing an acceptability threshold that supports the decision-making process.

【 授权许可】

Unknown