Renal Transplantation in the Setting of Prior Urinary Diversion: A Case of Poorly Differentiated Adenocarcinoma in an Ileal Conduit

Urology Case Reports

R. Goyal¹  X.J. Yang¹  J.P. Fryer²  J.C. Hairston³  R.S. Matulewicz³ 

[1] Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA;Department of Surgery, Kovler Organ Transplantation Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA;Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA;

关键词: Cystectomy;    Ileal conduit;    Neuroendocrine tumor;    Urinary diversion;   

DOI  :  10.1016/j.eucr.2015.01.001

来源: DOAJ

【 摘 要 】

Though rare, renal transplantation into a bowel containing urinary diversion is necessary in select clinical situations. Compared to renal transplant patients with functional native bladders, patients with urinary diversion have comparable long-term graft and patient survival rates. However, compounding the increased risk of malignancy in those on chronic immunosuppression are the inherent risks of urinary diversion. We present a case report of a high grade adenocarcinoma with neuroendocrine differentiation arising in an ileal conduit and discussion on the pathophysiology, management, and screening of this highly select population.

【 授权许可】

Unknown