Association between anesthesia duration and outcome in dogs with surgically treated acute severe spinal cord injury caused by thoracolumbar intervertebral disk herniation

Journal of Veterinary Internal Medicine

Joe Fenn¹  Karen R. Muñana²  Christopher L. Mariani²  Peter J. Early²  Franz J. Soebbeler³  Adriano Wang‐Leandro³  Hongyu Ru⁴  Sarah Moore⁵  Andrea Tipold⁵  Natasha J. Olby⁵  Nick D. Jeffery⁵ 

[1] Department of Clinical Science and Services Royal Veterinary College Hertfordshire United Kingdom;Department of Clinical Sciences College of Veterinary Medicine, North Carolina State University Raleigh North Carolina USA;Department of Small Animal Medicine and Surgery University of Veterinary Medicine Hannover Germany;Department of Statistics North Carolina State University Raleigh North Carolina USA;The Canine Spinal Cord Injury Consortium (CANSORT‐SCI);

关键词: canine;    extrusion;    hemilaminectomy;    prognosis;    surgery;   

DOI  :  10.1111/jvim.15796

来源: DOAJ

【 摘 要 】

Abstract Background Retrospective research recently identified a possible relationship between duration of surgery and outcome in severely affected dogs treated surgically for acute thoracolumbar intervertebral disk herniation (TL‐IVDH). Hypothesis That increased duration of surgery is associated with poorer outcome in dogs with absent pain perception treated surgically for TL‐IVDH. Animals Two hundred ninety‐seven paraplegic dogs with absent pain perception surgically treated for acute TL‐IVDH. Methods Retrospective cohort study. Medical records of 5 institutions were reviewed. Inclusion criteria were paraplegia with absence of pain perception, surgical treatment of TL‐IVDH, and 1‐year postoperative outcome (ambulatory: yes or no). Canine data, outcome, and surgery and total anesthesia duration were retrieved. Results In this study, 183/297 (61.6%) dogs were ambulatory within 1 year, 114 (38.4%) dogs failed to recover, including 74 dogs (24.9%) euthanized because of progressive myelomalacia. Median anesthesia duration in dogs that regained ambulation within 1 year of surgery (4.0 hours, interquartile range [IQR] 3.2‐5.1) was significantly shorter than those that did not (4.5 hours, IQR 3.7‐5.6, P = .01). Multivariable logistic regression demonstrated a significant negative association between both duration of surgery and total anesthesia time and ambulation at 1 year when controlling for body weight and number of disk spaces operated on. Conclusions and Clinical Importance Findings support a negative association between increased duration of anesthesia and outcome in this group of dogs. However, the retrospective nature of the data does not imply a causal relationship.

【 授权许可】

Unknown