Expanding Diversity of Susceptible Hosts in Peste Des Petits Ruminants Virus Infection and Its Potential Mechanism Beyond

Frontiers in Veterinary Science

Meera Prajapati¹  Yongxi Dou²  Zhidong Zhang³  Zhongxiang Liang⁴  Rui Zhang⁴  Yanmin Li⁴ 

[1] Animal Health Research Division, Nepal Agricultural Research Council, Lalitpur, Nepal;CAAS-ILRI Joint Laboratory for Ruminant Disease Control, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Sciences, Lanzhou, China;College of Life Science and Technology, Southwest Minzu University, Chengdu, China;State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Sciences, Lanzhou, China;

关键词: Morbillivirus;    peste des petits ruminants;    peste des petits ruminants virus;    susceptible hosts;    expanding;    potential mechanism;   

DOI  :  10.3389/fvets.2020.00066

来源: DOAJ

【 摘 要 】

Peste des petits ruminants (PPR) is a severe respiratory and digestive tract disease of domestic small ruminants caused by PPR virus (PPRV) of the genus Morbillivirus. Although the primary hosts of PPRV are goats and sheep, the host range of PPRV has been continuously expanding and reported to infect various animal hosts over the last decades, which could bring a potential challenge to effectively control and eradicate PPR globally. In this review, we focused on current knowledge about host expansion and interspecies infection of PPRV and discussed the potential mechanisms involved.

【 授权许可】

Unknown