Post‐coronavirus disease 2019 organizing pneumonia confirmed pathologically by video‐assisted thoracoscopic surgery

Respirology Case Reports

Shuji Haraguchi¹  Akira Hebisawa²  Seiji Igarashi³  Hirotaka Ono⁴  Keishi Sugino⁴  Eiyasu Tsuboi⁴ 

[1] Department of Chest Surgery Tsuboi Hospital Koriyama City Japan;Department of Clinical Pathology Asahi Central Hospital Asahi Japan;Department of Diagnostic Pathology Tsuboi Hospital Koriyama City Japan;Department of Respiratory Medicine Tsuboi Hospital Koriyama City Japan;

关键词: coronavirus disease 2019;    corticosteroid;    organizing pneumonia;    severe acute respiratory syndrome coronavirus 2;    video‐assisted thoracoscopic surgery;   

DOI  :  10.1002/rcr2.871

来源: DOAJ

【 摘 要 】

Abstract Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2, has become a global pandemic. Many survivors of serious COVID‐19 pneumonia have long‐term residual pulmonary disease. However, there is little documentation of the histopathological characteristics of lung sequelae post‐COVID‐19 and effective treatments. We present two Japanese cases of lung sequelae post‐COVID‐19. The patients were histopathologically diagnosed with organizing pneumonia (OP) or OP with fibrosis and no diffuse alveolar damage on video‐assisted thoracoscopic surgery. Case 1, who had been diagnosed with OP, was successfully treated with corticosteroid and other immunosuppressive agents over a 6‐month period. Although case 2, who had been diagnosed with OP with fibrosis, had a partial and unsatisfactory response to immunosuppressive agents, the patient responded to antifibrotic treatment including nintedanib.

【 授权许可】

Unknown