Ultrasensitive (Co)polymers Based on Poly(methacrylamide) Structure with Fining-Tunable pH Responsive Value

Molecules

Wei Li¹  Po Li¹  Xiaonan Huang¹  Haiming Fan²  Hui Li² 

[1] Department of Chemistry, Capital Normal University, 105 West 3rd Ring North Rd, Beijing 100048, China;Shandong Provincial Key Laboratory of Oilfield Chemistry, School of Petroleum Engineering, China University of Petroleum (East China), Qingdao 266580, China;

关键词: fine-tuning;    pH responsive;    poly(methacrylamide)s;    phase transition;   

DOI  :  10.3390/molecules23081870

来源: DOAJ

【 摘 要 】

Novel pH responsive copolymers with tertiary amine groups were prepared by free radical polymerization with 2-(dialkylamino)ethyl methacrylate monomers. These polymers were pH sensitive with the ability to be responsively fine-tuned in aqueous solution, which was proven through titration, transmittance measurements, and proton nuclear magnetic resonance spectroscopy. The polymers were soluble in water at low pH values, induced by electrostatic repulsion between amine groups, and aggregated above their pKa value due to the hydrophobic effect of the alkyls. The pH responsive values were precisely tuned from 7.4 to 4.8 by increasing the hydrophobic monomer ratio. Our work provides a novel approach for the development of ultrasensitive pH-responsive polymers for application in biomedical materials.

【 授权许可】

Unknown