Anaphylaxis

Allergy, Asthma & Clinical Immunology

Anne K. Ellis¹  Timothy K. Vander Leek²  Harold Kim³  David Fischer³ 

[1] Queen’s University;University of Alberta;Western University;

关键词: Anaphylaxis;    Diagnosis;    Acute management;    Epinephrine;    Long-term management;    Anaphylaxis action plan;   

DOI  :  10.1186/s13223-018-0283-4

来源: DOAJ

【 摘 要 】

Abstract Anaphylaxis is an acute, potentially fatal systemic allergic reaction with varied mechanisms and clinical presentations. Although prompt recognition and treatment of anaphylaxis are imperative, both patients and healthcare professionals often fail to recognize and diagnose early signs and symptoms of the condition. Clinical manifestations vary widely; however, the most common signs are cutaneous symptoms, including urticaria, angioedema, erythema and pruritus. Immediate intramuscular administration of epinephrine into the anterolateral thigh is first-line therapy, even if the diagnosis is uncertain. The mainstays of long-term management include specialist assessment, avoidance measures, and the provision of an epinephrine auto-injector and an individualized anaphylaxis action plan. This article provides an overview of the causes, clinical features, diagnosis and acute and long-term management of this serious allergic reaction.

【 授权许可】

Unknown