Сlinical, functional and morphological results of diabetic macular edema antiangiogenic treatment in patients with diabetes mellitus type two

Oftalʹmologiâ

I. V. Vorobieva¹  L. K. Moshetova¹  D. A. Merkushenkova¹  V. I. Alekhnovich²  E. V. Parfenova³  P. I. Makarevich³ 

[1] ГБОУ ДПО РМАПО Министерства здравоохранения России;ФГБОУ ВПО МГТУ им. Н. Э. Баумана;ФГБОУ ВПО МГУ им. М. В. Ломоносова;

关键词: diabetic macular edema;    angiogenesis inhibitor;    vegf;   

DOI  :  10.18008/1816-5095-2013-1-50-55

来源: DOAJ

【 摘 要 】

Purpose: To evaluate of retinal morphology and function progress in patients with diabetes type 2 and DME consistent with the level of pathogenetic factor in tear fluid.Methods: The progress of visual acuity, retinal thickness and photosensitivity after ranibizumab intravitreal injection has been assessed.Results: Statistically significant increase in visual acuity, retinal photosensitivity, decrease of retinal thickness and VEGF A level was found in the tear fluid after injection. The correlation of VEGF level in tear fluid with visual acuity after procedure was found to be negative. Conclusion: Ranibizumab intravitreal injection is a pathogenic treatment leading to morphological and functional retinal state improvement.

【 授权许可】

Unknown