Endometriosis-associated epithelial ovarian cancer is a more complicated disease than we suspected before

Taiwanese Journal of Obstetrics & Gynecology

Wei-An Lai¹  Wen-Ling Lee¹  Wen-Hsun Chang²  Na-Rong Lee³  Shu-Huei Shen³  Szu-Ting Yang³  Peng-Hui Wang⁴ 

[1] Department of Nursing, Taipei Veterans General Hospital, Taipei, Taiwan;Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan;Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan;Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan;

关键词: Endometrioid adenocarcinoma;    Endometriosis;    Endometriosis-associated epithelial ovarian cancer;    Mucinous adenocarcinoma;   

DOI  :  

来源: DOAJ

【 摘 要 】

Objective: Endometriosis-associated epithelial ovarian cancer (EOC) often includes clear cell carcinoma and endometrioid-type carcinoma. Due to the low incidence of primary mucinous EOC and absence of association between endometriosis and primary mucinous EOC, we present an unusual endometriosis-associated mixed mucinous and endometrioid adenocarcinoma arising from the same ovary. Case report: A 54-year-old woman had an abdominal palpable mass for months. Medical and surgical history, as well as preoperative surveys was unremarkable, except of presence of a pelvic mass. She underwent an exploration laparotomy, and a 22-cm right ovarian tumor was found. Grossly, right ovarian tumor containing brownish cloudy cystic fluid 2450 ml and an apparent 4 × 4 × 2 cm-sized papillary growth. Microscopically, a confluent glandular and infiltrative pattern presented endometrioid adenocarcinoma, and cells with intracytoplasmic mucin and stratified elongated epithelial cells presented mucinous adenocarcinoma. Surgico-pathological stage was FIGO IIIA due to tumor invading to the peritoneum above the pelvis. Postoperatively, the dose-dense chemotherapy was applied with uneventful outcome. Conclusion: This is a rare case, composed with mixed mucinous and endometrioid adenocarcinoma of the same ovary, suggesting that careful pathological diagnosis of endometriosis-associated EOC is needed.

【 授权许可】

Unknown