The application of sudoscan for screening microvascular complications in patients with type 2 diabetes

PeerJ

Jiaqi Huang¹  Guishan Chen¹  Kun Lin¹  Yixi Wu¹  Shuo Liu²  Qiong Zeng² 

[1] Department of Endocrinology, The First Affiliated Hospital of Shantou University Medical College, Shantou, China;Department of Neurology, The First Affiliated Hospital of Shantou University Medical College, Shantou,China;

关键词: Sudoscan;    Diabetic microvascular complications;    Diabetic peripheral neuropathy;    Diabetic kidney disease;    Diabetic retinopathy;   

DOI  :  10.7717/peerj.13089

来源: DOAJ

【 摘 要 】

The aim of the study was to evaluate the performance of sudoscan in screening diabetic microvascular complications in patients with type 2 diabete mellitus (T2DM). 515 patients with T2DM aged from 23 to 89 years were included for analysis in our study. The mean age was 60.00 ± 11.37 years and the mean duration of T2DM was 8.44 ± 7.56 years. Electrochemical skin conductance (ESC) in hands and feet was evaluated by SUDOCAN. Diabetic peripheral neuropathy (DPN) was diagnosed in 378 patients (44.3%), diabetic kidney disease (DKD) in 161 patients (31.26%), diabetic retinopathy (DR) in 148 patients (28.74%). Hands and feet ESC was significantly and independently associated with the presence of DPN, DKD and DR. Patients with a lower ESC (<60 µS) had 5.63-fold increased likelihood of having DPN, 4.90-fold increased likelihood of having DKD, 1.01-fold increased likelihood of having DR, than those with a higher ESC. Age, duration of T2DM, smoking, renal function and vibration perception thresholds were negatively correlated with ESC. Sudoscan parameters were correlated with diabetic microvascular complications, especially with DPN. Sudoscan could be an effective screening tool in primary health care for early screening microvascular complications.

【 授权许可】

Unknown