Sex-Specific Outcomes in Patients with Acute Coronary Syndrome

Journal of Clinical Medicine

Dirk Westermann¹  Christina Magnussen¹  JohannesT. Neumann¹  Stefan Blankenberg¹  NilsA. Sörensen¹  Alina Goßling¹ 

[1] Department of Cardiology, University Heart and Vascular Center Hamburg, Hamburg 20246, Germany;

关键词: acute coronary syndrome;    sex;    myocardial infarction;    ST-elevation myocardial infarction (STEMI);    non-STEMI (NSTEMI);    unstable angina pectoris;   

DOI  :  10.3390/jcm9072124

来源: DOAJ

【 摘 要 】

Sex differences in patients with acute coronary syndrome (ACS) are a matter of debate. We investigated sex-specific differences in the incidence, outcomes, and related interventions in patients diagnosed with ACS in Germany over the past decade. All ACS cases from 2005 to 2015 were collected. Procedures and inhospital mortality were assessed by sex. Age-adjusted incidence rates were calculated. In total, 1,366,045 females and 2,431,501 males presenting with ACS were recorded. Females were older than males (73.1 vs. 66.4 years of age), had a longer mean hospital stay (7.7 vs. 6.9 days), and less frequently underwent coronary angiographies (55% vs. 66%) and coronary interventions (35% vs. 47%). The age-adjusted incidence rate of ACS was lower in females than in males, and decreased in both sexes from 2005 to 2015. The age-adjusted inhospital mortality rate was substantially higher in females than in males, but decreased in both sexes over time (in females, from 87 to 71 cases per 1000 person years; in males, from 57 to 51 cases per 1000 person years). In conclusion, we reported sex differences in the incidence, treatment, and outcomes of ACS patients in Germany within the past decade. Women had a substantially higher mortality rate and lower rate of coronary interventions.

【 授权许可】

Unknown