Hydroxyapatite Mineralization on the Calcium Chloride Blended Polyurethane Nanofiber via Biomimetic Method

Nanoscale Research Letters

关键词: Polyurethane;    Electrospinning;    Nanofibers;    Simulated body fluid;    Bioactivity;   

DOI  :  

来源: DOAJ

【 摘 要 】

Abstract

Polyurethane nanofibers containing calcium chloride (CaCl₂) were prepared via an electrospinning technique for the biomedical applications. Polyurethane nanofibers with different concentration of CaCl₂ were electrospun, and their bioactivity evaluation was conducted by incubating in biomimetic simulated body fluid (SBF) solution. The morphology, structure and thermal properties of the polyurethane/CaCl₂ composite nanofibers were characterized by means of scanning electron microscopy (SEM), field-emission scanning electron microscopy, energy dispersive X-ray spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy and thermogravimetry. SEM images revealed that the CaCl₂ salt incorporated homogeneously to form well-oriented nanofibers with smooth surface and uniform diameters along their lengths. The SBF incubation test confirmed the formation of apatite-like materials, exhibiting enhanced bioactive behavior of the polyurethane/CaCl₂ composite nanofibers. This study demonstrated that the electrospun polyurethane containing CaCl₂ composite nanofibers enhanced the in vitro bioactivity and supports the growth of apatite-like materials.

【 授权许可】

Unknown