Unilateral resection of the anterior medial temporal lobe impairs odor identification and valence perception

Frontiers in Psychology

Stephanie Anja Juran¹  Mats J Olsson¹  Michael eGeigant³  Johan N Lundström⁴  Eva eKumlien⁵  Mats eFredrikson⁵  Fredrik eÅhs⁵ 

[1] Karolinska Institutet;Monell Chemical Senses Center;Stockholm County Council;University of Pennsylvania;Uppsala University;

关键词: Olfactory Perception;    brain lateralization;    Temporal Lobe Epilepsy (TLE);    odor valence;    Anterior medial temporal lobe;    Amygdalo-Hyppocampectomy;   

DOI  :  10.3389/fpsyg.2015.02015

来源: DOAJ

【 摘 要 】

The anterior medial temporal lobe (TL), including the amygdala, has been implicated in olfactory processing, e.g. coding for intensity and valence, and seems also involved in memory. With this background, the present study evaluated whether anterior medial TL-resections in temporal lobe epilepsy affected intensity and valence ratings, as well as free and cued identification of odors. These aspects of odor perception were assessed in thirty-one patients with unilateral anterior medial TL-resections (17 left, 14 right) and 16 healthy controls. Results suggest that the anterior medial TL is in particular necessary for free, but also cued, odor identification. TL resection was also found to impair odor valence, but not intensity ratings. Left resected patients rated nominally pleasant and unpleasant as more neutral suggesting a special role for the left anterior temporal lobe in coding for emotional saliency in response to odors.

【 授权许可】

Unknown