In Vivo Neural Interfaces—From Small- to Large-Scale Recording

Frontiers in Nanotechnology

Xiaojian Li¹  Chunshan Deng¹  Chunzhi Cai²  Bingjie Zhang³ 

[1] CAS Key Laboratory of Brain Connectome and Manipulation, The Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, China;Division of Biological and Environmental Sciences and Engineering (BESE), King Abdullah University of Science and Technology, Thuwal, Saudi Arabia;Nano Science and Technology Institute, University of Science and Technology of China, Suzhou, China;

关键词: in vivo;    neural interface;    large scale;    neural electrode;    brain–machine interface;   

DOI  :  10.3389/fnano.2022.885411

来源: DOAJ

【 摘 要 】

Brain functions arise from the coordinated activation of neuronal assemblies distributed across multiple brain regions. The electrical potential from the neuron captured by the electrode can be processed to extract brain information. A large number of densely and simultaneously recorded neuronal potential signals from neurons spanning multiple brain regions contribute to the insight of specific behaviors encoded by the neural ensembles. In this review, we focused on the neural interfaces developed for small- to large-scale recordings and discussed the developmental challenges and strategies in microsystem, electrode device, and interface material levels for the future larger-scale neural ensemble recordings.

【 授权许可】

Unknown