Indicators of cell and humoral immune response under pulmonary tuberculosis accompanied by eosinophilia

Bûlleten' Sibirskoj Mediciny

O. I. Novoseltseva¹  Ye. P. Stepanova¹  O. I. Urazova²  O. V Voronkova²  K. O. Mikheyeva²  Yu. V. Kolobovnikova²  O. V. Filinyuk²  M. V. Ignatov²  V. V. Novitsky² 

[1] ОГУЗ «Областная туберкулезная клиническая больница», г. Томск;Сибирский государственный медицинский университет, г. Томск;

关键词: pulmonary tuberculosis;    eosinophils;    lymphocytes;    cytokines;   

DOI  :  10.20538/1682-0363-2012-1-39-45

来源: DOAJ

【 摘 要 】

The data of the comparative analysis of separate parameters of cell and humoral chains of immune response in patients suffering from pulmonary tuberculosis accompanied by eosinophilia has been presented in the article.With involving contemporary immunological methods of research, it has been stated that tuberculosis infection in combination with eosinophilic blood reaction is accompanied by marked cytokine imbalance, characterized by increase in the concentration of IL-5 (mediator with anti-inflammatory activity) in blood serum against the background of low serum level of the key anti-tuberculosis cytokine — IFN-γ.

【 授权许可】

Unknown