期刊论文详细信息
Open Medicine
Trypsinogen activation peptide induces HMGB1 release from rat pancreatic acinar cells
Bai Liang1  Liu Yao1  Wei Wei1  Tian Fei1  Wang Guoliang2  Liu Yan2  Dui Danhua3 
[1] China Department of Hepatobiliaropancreatic Surgery, Affiliated Hospital of Zunyi Medical College, Zunyi563003, China;Department of Hepatobiliaropancreatic Surgery, Guizhou Provincial People’s Hospital, Guiyang, 550002, China;Department of Hepatopancreatobiliary Surgery, Affiliated Hospital of Zunyi Medical, College, Zunyi563003, China;
关键词: Pancreatic acinar cell;    Trypsinogen activation peptide;    High mobility group box-1;    Ethyl pyruvate;    Rat;   
DOI  :  10.1515/med-2017-0043
来源: DOAJ
【 摘 要 】

The development of acute pancreatitis (AP) is associated with intracellular events in pancreatic cells, as well as with early and late inflammatory responses; however, their underlying mechanisms remain unclear. This study investigated trypsinogen activation peptide (TAP)-induced release of high mobility group box-l (HMGB1) from pancreatic acinar cells and how ethyl pyruvate (EP) affects this release.

【 授权许可】

Unknown   

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