Invasive Fungal Disease, Isavuconazole Treatment Failure, and Death in Acute Myeloid Leukemia Patients

Emerging Infectious Diseases

关键词: aspergillosis;    fungal co-infection;    invasive fungal disease;    isavuconazole;    treatment failure;    mucormycosis;   

DOI  :  10.3201/eid2509.190598

来源: DOAJ

【 摘 要 】

We present 2 fatal cases of invasive fungal disease with isavuconazole treatment failure in immunocompromised patients: one with a TR34-L98H azole–resistant Aspergillus fumigatus isolate and the other a Rhizomucor–A. fumigatus co-infection. Such patients probably require surveillance by galactomannan antigen detection and quantitative PCRs for A. fumigatus and Mucorales fungi.

【 授权许可】

Unknown