Synthesis of 8-Aminoquinoline Amides of Ursonic and Oleanonic Acid

Molbank

Vladislavs Kroškins¹  Māris Turks¹  Jevgeņija Lugiņina¹  Anatoly Mishnev² 

[1] Institute of Technology of Organic Chemistry, Faculty of Materials Science and Applied Chemistry, Riga Technical University, P. Valdena Str. 3, LV-1048 Riga, Latvia;Latvian Institute of Organic Synthesis, Aizkraukles Str. 21, LV-1006 Riga, Latvia;

关键词: triterpenoids;    oleanolic acid;    ursolic acid;    8-aminoquinoline amides;   

DOI  :  10.3390/M1361

来源: DOAJ

【 摘 要 】

8-Aminoquinoline amides of 3-oxo-olean-12-en-28-oic acid and 3-oxo-urs-12-en-28-oic acid were obtained and characterized by ¹H, ¹³C-NMR and single crystal X-ray analysis. The used triterpenoic acids are oxidized forms of naturally occurring oleanolic acid and ursolic acids. Such types of derivatives are known for their anticancer and antiviral activities. On the other hand, 8-aminoquinoline amides are frequently used for transition metal complexation that is applicable for both C-H activation processes and biological activity studies.

【 授权许可】

Unknown